doi: 10.2340/00015555-0639. Tattoo-associated skin reaction: the importance of an early diagnosis and proper treatment. Tattoo-associated pseudolymphomatous reaction and its successful treatment with hydroxychloroquine. Caused by sensitivity to a substance in the tattoo ink, this is a delayed reaction — it doesn't occur right after getting the tattoo. You've developed an allergy to the ink. In total 139 patients were included within the studies. Box 30.001, 9700 RB Groningen, The Netherlands. Pseudolymphomatous Allergy. Awareness of this type of reaction to tattoo pigment can help prevent erroneous diagnosis of lymphoma. Simultaneous pseudolymphomatous and lichenoid tattoo reactions triggered by re‐tattooing T. A. Chave Departments of Dermatology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK Tattoo-associated pseudolymphomatous reaction and its successful treatment with hydroxychloroquine. Topical or intralesional corticosteroid therapy may also be used but recurrences are common. The above image shows (left) a pseudolymphomatous reaction in the red-pigmented region of a tattoo and (right) lesion resolution following four treatments with a Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser.. Such a delay indicates that this is a pseudolymphomatous allergy. One of the cases showed histologic features of Spiegler-Fendt pseudolymphoma. 3. Annalisa Patrizi, Beatrice Raone, Francesco Savoia, Francesco Bacci, Alessandro Pileri, Carlotta Gurioli and Iria Neri DOI: 10.2340/00015555-0639 Abstract. According to cases reported by other authors, surgical excision of the pseudolymphomatous reaction is the most effective treatment [7,10,11,[14][15] [16] [17]. ... Hsu WT. This … Most reactions are characterized by flesh … 5). A punch biopsy was performed and the histology showed a pseudolymphomatous reaction. Tattoo-associated Pseudolymphomatous Reaction and its Successful Treatment with Hydroxychloroquine. Pseudolymphomatous reactions These are usually the result of a delayed hypersensitivity reaction to tattoo pigment. The current evidence for the treatment for the above is presented. Most of the time, the cause of this allergy is red ink. Case description The first case concerns a 57yearold female, who developed an itching swelling in the red part of a tattoo on the left arm. Three cases with pseudolymphomatous hypersensitivity reaction to tattoo pigment are described. Signs and symptoms of an infection and allergic reaction vary. Acta Derm Venereol. Again, red pigment is the main cause but … Disorders as varied as Jessner's lymphocytic infiltrate, lymphomatoid drug eruptions, lymphomatoid contact dermatitis, lymphomatoid photoallergic reactions including actinic reticuloid, and pseudolymphomatous angiokeratoma (also known as acral pseudolymphomatous angiokeratoma of children or APACHE) have been lumped into this latter T-cell category. A few months after you get a tattoo there may be a rash, redness and other irritations. This review systematically analyses the different subsets of red tattoo reactions including lichenoid, dermatitis, granulomatous, pseudolymphomatous and miscellaneous reactions. This treatment does not appear immediately, but after you get a tattoo. Histology of a punch biopsy showed a pseudolymphomatous reaction. [Google Scholar] Tattoo reactions can be clinically challenging to diagnose and treat. We present a case of a biopsy-proven granulomatous reaction to purple tattoo ink that clinically mimicked lichen planus. The histologic pattern of these reactions varies from a diffuse lymphohis- tiocytic infiltrate with an admixture of plasma cells and eosinophils,l-6 to tichenoid reactions simulat- ing lichen planus,7-to sarcoidal granulomas2'1 A pseudolymphomatous reaction to tattoo pigment was first described by one of us1in a textbook. Pseudolymphomatous allergic reaction. Clinically, pseudolymphomatous reactions are characterized by plum to violet hued firm nodules and are often solitary or localized. However, in the case of tattoo reactions, multiple lesions can occur. Authoritative facts from DermNet New Zealand. The signs arising are similar to the lichen planus. 1,8 Two cases of reactions to tattoos were reported here. Examples of delayed reactions include allergic contact dermatitis, granulomatous dermatitis, lichenoid dermatitis and pseudolymphomatous reactions [4, 5]. Pseudolymphomatous reaction: It is the delayed hypersensitivity reaction to tattoo pigment. It will present with redness and slight swelling. The current evidence for the treatment for the above is presented. Pseudolymphomatous allergic reaction. 2009. Acta Derm Venereol. Patrizi A, Raone B, Savoia F, Bacci F, Pileri A, Gurioli C, et al. In this article we discuss the different types of reactions to red tattoo pigment with a review of the literature with regards to the treatment for each pattern. Simultaneous pseudolymphomatous and lichenoid tattoo reactions triggered by re‐tattooing Simultaneous pseudolymphomatous and lichenoid tattoo reactions triggered by re‐tattooing Chave, T. A.; Mortimer, N. J.; Johnston, G. A. Rijlaarsdam JU, Bruynzeel DP, Vos W, Meijer CJ, Willemze R. Immunohistochemical studies of lymphadenosis benigna cutis occurring in a tattoo. For recurrent lesions, treatment is intralesional steroid injections (triamcinolone 5mg/ml on face, 10mg/ml elsewhere, to start). If applicable, stop the offending agent (medication, topical agent). Patrizi A, Raone B, Savoia F, et al. 2009; 89:327–8. 1. Results. Although the complications associated with tattooing and tattoo removal are often mild and self-limited, significant adverse events are possible with both. Tattoo-associated pseudolymphomatous reaction and its successful treatment with hydroxychloroquine. There is no bad smell, fluid discharge or fever during an allergic reaction. Initially, she was treated with pimecrolimus 1% cream for 8 weeks, which was then combined with metronidazole cream for 4 weeks, with the initial diagnosis of UV-triggered rosacea, without improvement. 2009;89(3):327-8. doi: 10.2340/00015555-0639. Carlotta Gurioli and Iria Neri doi: 10.2340/00015555-0639 Abstract reaction and its successful treatment with hydroxychloroquine and... 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